Scientists have uncovered a natural braking system that helps the immune system switch off inflammation and prevent harmful immune cells from building up. Boosting this pathway in people reduced inflammation-related immune changes and sped up pain relief, pointing toward potential new treatments for chronic inflammatory diseases.

First author Dr. Olivia Bracken (UCL Department of Ageing, Rheumatology and Regenerative Medicine) said: "Our findings reveal a natural pathway that limits harmful immune cell expansion and helps calm inflammation more quickly.

“Targeting this mechanism could lead to safer treatments that restore immune balance without suppressing overall immunity. With chronic inflammation ranked as a major global health threat, this discovery opens a promising avenue for new therapies.”

    • yestalgia@lemmy.world
      5·
      4 days ago

      Yes. Studies show that nonsteroidal anti-inflammatory drugs like Advil and Tylenol can actually supress gains in the gym if taken in excess because the natural muscle breakdown, inflammation, and response mechanism is blunted. Same is true for ice baths. So, sometimes swelling and inflammation can be a good thing that we want to occur.

      Also staying on prednisone and other steroids too long to supress inflammation leads to all kinds of issues.

      • village604@adultswim.fanEnglish
        2·
        3 days ago

        Tylenol is not an NSAID. It doesn’t work on inflammation.

        Also, there was a study a year or so ago that found evidence that Ibuprofen after working out helped speed recovery times.

        • yestalgia@lemmy.world
          2·
          1 day ago

          Speeding recovery times has a tradeoff though. It may be negligible but I heard on an exercise science podcast of some kind that it blunts the recovery process so if maximizing muscle growth is your goal, don’t overdo nsaids.

          However, like you said, if you’re an NFL athlete during the season then recovery is the priority over muscle growth and then ice baths and nsaids and inflammation reducing things are worth the trade off.

          My mistake on Tylenol being an nsaid. Obvious hindsight. Brain fart.